Performance comparison of locally available single dose dry powder Inhalers using computational fluid modeling and cascade impactor testing

Abstract

The study was focused on evaluating the performance of locally available single dose dry powder inhalers using computational fluid dynamics (CFD) and cascade impactor CI). CFD was used to assess the behavior of the air flow through the inhalers when the patient inhales. CI was used to assess what happens inside the patient's respiratory tract after inhaling. Results predicted in CFD clearly reflected from CI testing.