Abstract:
The design and analysis of a Micro Electromechanical
System-based (MEMS-based) Transdermal Drug Delivery
System are presented in the research article. A conceptual design
for the delivery of Levodopa was proposed by the authors. Major
components of the system were identified as a microfluidic pump,
microneedle array and the microfluidic channels connecting the
system. The working principles of these components were selected
according to the persisting requirements and design considerations.
Simulations were conducted to evaluate the performance
and to optimize the design of the system. A fabrication method
for the system was proposed by the authors as a stacked layer.
The results of the simulations conducted were presented. The
simulations show positive results with the performance of the
system and do not suggest a mode of mechanical failure of the
system at the given boundary conditions. The paper concludes
with recommendations for future work.
